Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed) | PAR 23 184

Opportunity Information: Apply for PAR 23 184

The Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access opportunity (PAR-23-184) is an NIH-wide access mechanism that lets approved research projects use CIDR as a centralized, specialized genomics resource. Instead of providing a traditional pot of money to build a lab locally, this program is set up to give investigators access to high-throughput genotyping, next-generation sequencing, and related statistical genetics support that would be difficult, inefficient, or too costly for many individual laboratories to perform on their own. The core goal is to accelerate discovery of genes and genetic variants that influence human health and disease, and to strengthen existing specimen collections by adding high-quality genotype or sequencing data to well-phenotyped samples stored in biorepositories.

CIDR is positioned as a service center that stays current with leading platforms and best practices, and it provides both laboratory production work and supporting statistical genetics expertise. Projects that fit well are typically those with strong phenotyping and clear scientific questions where large-scale genotyping or sequencing can meaningfully advance gene discovery, variant interpretation, risk modeling, or related analyses. Another strong use case is enriching existing cohorts or repository collections by generating genomic data that can be linked to clinical, behavioral, environmental, or other phenotype data already collected. The intent is not to fund a clinical trial under this announcement (it is explicitly "Clinical Trial Not Allowed"), but to support genomic data generation and analytical support that complements robust, hypothesis-driven or discovery-focused human genetics studies.

This is a discretionary NIH grant opportunity managed by the National Human Genome Research Institute (NHGRI), but it is described as NIH-wide, meaning it is meant to serve the broader NIH research community rather than a single institute's portfolio. Applicants are directed to CIDR's website (http://www.cidr.jhmi.edu) for current information on available services and platforms, which is important because the specific technologies and operational offerings can change over time as methods evolve.

Eligibility is broad and includes many common domestic applicant types such as state, county, and local governments; public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses) as well as small businesses; independent school districts; special district governments; and public housing authorities/Indian housing authorities. It also explicitly includes a wide range of additional eligible applicants, such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISI institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), federally recognized tribal governments, and tribal organizations or tribal governments that are not federally recognized. Faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, regional organizations, and non-U.S. (foreign) entities are also listed as eligible, signaling that the program is intended to be accessible to a diverse set of institutions and research settings.

From the source details provided, the opportunity falls under a grant funding instrument and is categorized under education, environment, and health-related activity areas, with CFDA/assistance listing numbers 93.113, 93.121, 93.172, 93.399, and 93.853. The original closing date is listed as 2026-07-08. The listing does not specify an award ceiling or expected number of awards in the provided fields, which is consistent with a resource-access style program where support is often delivered as services rather than a standard capped budget per award. In practical terms, the key takeaway is that this opportunity is about gaining access to CIDR's high-throughput genomic production and statistical genetics capabilities to generate or expand high-quality genomic datasets that can drive human genetics and genomics research forward, while staying within a non-clinical-trial scope.

• The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.399, 93.853.
• This funding opportunity was created on 2023-05-26.
• Applicants must submit their applications by 2026-07-08. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 23 184

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