Opportunity Information: Apply for RFA AI 24 006
The Centers for Research in Emerging Infectious Diseases (CREID) Network funding opportunity (RFA-AI-24-006) is a National Institutes of Health (NIH) cooperative agreement (U01) intended to support Research Centers that focus on re-emerging and emerging infectious diseases around the world, especially in places where outbreaks are most likely to occur. The goal is to build and sustain a coordinated network that can generate new scientific knowledge before crises happen, while also being able to pivot quickly and mount a strong, organized research response during outbreaks. This is not a clinical trial mechanism, which means applicants should design research that advances understanding of pathogens, transmission, ecology, and preparedness without proposing clinical trial activities under this award.
A defining feature of the CREID program is its emphasis on a One Health approach. In practice, this means projects are expected to treat human health, animal health, and environmental conditions as linked pieces of the same system. Rather than studying human infection in isolation, the network encourages integrated work that might include animal reservoirs and vectors, land use and climate factors, environmental sampling, and social or behavioral drivers that influence how outbreaks start and spread. The intent is to support multi- and interdisciplinary teams that can connect these domains and translate that integration into better outbreak prediction, prevention, and response.
The opportunity is structured around Research Centers that will operate as part of a broader, collaborative network rather than as standalone, independent projects. NIH is explicitly looking for applicants who will coordinate, collaborate, and cooperate across the CREID Network, including during outbreak events when rapid research action is needed. This implies that funded centers should be prepared to share information, align methods where appropriate, contribute to network-wide activities, and participate in joint efforts that strengthen the collective ability to respond quickly and effectively when new threats emerge.
Eligibility is broad and includes a wide range of domestic U.S. organizations and governmental entities, such as state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; and small businesses. The NOFO also highlights additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). That breadth reflects the program’s global outlook and its interest in building teams that can operate effectively across borders and sectors.
Key administrative details included in the source information are that this is a discretionary funding opportunity in the health category (CFDA 93.855), administered by NIH, with an original application closing date of June 21, 2024. The funding instrument is a cooperative agreement, which typically indicates substantial NIH involvement beyond standard grant oversight, often through coordination expectations, shared network goals, and active programmatic collaboration. The listed award ceiling is $350,000, signaling an upper limit referenced in the opportunity materials, and the record shows the notice was created on March 27, 2024.Apply for RFA AI 24 006
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers for Research in Emerging Infectious Diseases (CREID) Network (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
- This funding opportunity was created on 2024-03-27.
- Applicants must submit their applications by 2024-06-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): CREID Network Research Centers (RFA-AI-24-006)
What is the CREID Network funding opportunity (RFA-AI-24-006)?
The Centers for Research in Emerging Infectious Diseases (CREID) Network opportunity (RFA-AI-24-006) is a National Institutes of Health (NIH) cooperative agreement (U01) intended to support Research Centers focused on re-emerging and emerging infectious diseases worldwide, especially in areas where outbreaks are most likely to occur.
What is the main goal of the CREID program?
The goal is to build and sustain a coordinated network that can generate new scientific knowledge before public health crises happen, while also being able to pivot quickly and mount a strong, organized research response during outbreak events.
What kinds of diseases does CREID focus on?
CREID focuses on re-emerging and emerging infectious diseases around the world, with particular attention to settings where outbreaks are most likely to occur.
Is this opportunity meant to fund standalone projects, or networked Research Centers?
This opportunity is structured around Research Centers that operate as part of a broader, collaborative CREID Network. The intent is not to fund isolated, independent projects, but rather centers that coordinate and cooperate across the network.
What does it mean that this is a cooperative agreement (U01)?
A cooperative agreement typically indicates substantial NIH involvement beyond standard grant oversight. In this program, it aligns with expectations for coordination, shared network goals, and active programmatic collaboration among funded centers and the NIH.
Does NIH expect collaboration across funded centers?
Yes. NIH is explicitly looking for applicants who will coordinate, collaborate, and cooperate across the CREID Network, including during outbreak events that require rapid research action.
What does being part of the CREID Network imply for funded centers?
Funded centers should be prepared to share information, align methods where appropriate, contribute to network-wide activities, and participate in joint efforts that strengthen collective readiness and response when new threats emerge.
What is the One Health approach, and why is it central to CREID?
One Health treats human health, animal health, and environmental conditions as connected parts of the same system. CREID emphasizes integrated research that links these domains to improve outbreak prediction, prevention, and response.
What are examples of the types of integrated topics CREID encourages under One Health?
CREID encourages work that may include animal reservoirs and vectors, land use and climate factors, environmental sampling, and social or behavioral drivers that influence how outbreaks start and spread, rather than focusing on human infection alone.
What kind of research is this funding meant to support?
This funding is meant to support research that advances understanding of pathogens, transmission, ecology, and preparedness, and that can generate knowledge ahead of crises while enabling a rapid, organized research posture during outbreaks.
Is this a clinical trial funding mechanism?
No. This is not a clinical trial mechanism. Applicants should design research that advances scientific understanding and preparedness without proposing clinical trial activities under this award.
What does it mean that applicants should not propose clinical trial activities under this award?
Based on the opportunity description, applicants should avoid proposing clinical trial activities as part of the work supported by this U01, and should instead focus on research related to pathogens, transmission, ecology, and outbreak preparedness/response capabilities.
Who administers this opportunity?
This opportunity is administered by the National Institutes of Health (NIH).
What is the category and assistance listing information provided for this opportunity?
It is described as a discretionary funding opportunity in the health category, with CFDA 93.855 listed in the source information.
What is the application closing date listed for this opportunity?
The original application closing date listed is June 21, 2024.
What is the listed award ceiling?
The listed award ceiling is $350,000, indicating an upper limit referenced in the opportunity materials.
When was the opportunity record created?
The record shows the notice was created on March 27, 2024.
What types of U.S. domestic organizations are eligible to apply?
Eligibility is broad and includes many domestic U.S. organizations and governmental entities, such as state, county, city, or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; and small businesses.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized tribal governments are eligible, and tribal organizations that are not federally recognized are also included in the listed eligible applicant types.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The opportunity highlights Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISI); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based and community-based organizations eligible?
Yes. Faith-based or community-based organizations are specifically mentioned among additional eligible applicant types.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are included among the additional eligible applicant types highlighted in the opportunity description.
Are applicants from U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly included in the additional eligible applicant types.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. Non-U.S. entities (foreign organizations) are listed as eligible applicant types, which aligns with the program's global outlook.
Why does the opportunity include such broad eligibility?
The breadth of eligibility is described as reflecting the program's global outlook and its interest in building teams that can operate effectively across borders and sectors.
What kind of teams is CREID trying to support?
CREID aims to support multi- and interdisciplinary teams that can connect human health, animal health, and environmental conditions, and translate that integration into improved outbreak prediction, prevention, and response.
Does the program emphasize preparedness before outbreaks as well as response during outbreaks?
Yes. A core aim is to generate new scientific knowledge before crises happen while also maintaining the ability to pivot quickly and conduct an organized research response during outbreak events.
What does "rapid research action" during outbreaks mean in the context provided?
In the context provided, it refers to the network being ready to pivot quickly and mount a strong, organized research response during outbreak events, supported by coordination and collaboration across the CREID Network.
Does the opportunity suggest that centers should align methods across the network?
Yes. The description indicates centers should be prepared to align methods where appropriate as part of network coordination and collective response efforts.
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