Centers for Research in Emerging Infectious Diseases (CREID) Network (U01 Clinical Trial Not Allowed) | RFA AI 24 006

Opportunity Information: Apply for RFA AI 24 006

The Centers for Research in Emerging Infectious Diseases (CREID) Network funding opportunity (RFA-AI-24-006) is a National Institutes of Health (NIH) cooperative agreement (U01) intended to support Research Centers that focus on re-emerging and emerging infectious diseases around the world, especially in places where outbreaks are most likely to occur. The goal is to build and sustain a coordinated network that can generate new scientific knowledge before crises happen, while also being able to pivot quickly and mount a strong, organized research response during outbreaks. This is not a clinical trial mechanism, which means applicants should design research that advances understanding of pathogens, transmission, ecology, and preparedness without proposing clinical trial activities under this award.

A defining feature of the CREID program is its emphasis on a One Health approach. In practice, this means projects are expected to treat human health, animal health, and environmental conditions as linked pieces of the same system. Rather than studying human infection in isolation, the network encourages integrated work that might include animal reservoirs and vectors, land use and climate factors, environmental sampling, and social or behavioral drivers that influence how outbreaks start and spread. The intent is to support multi- and interdisciplinary teams that can connect these domains and translate that integration into better outbreak prediction, prevention, and response.

The opportunity is structured around Research Centers that will operate as part of a broader, collaborative network rather than as standalone, independent projects. NIH is explicitly looking for applicants who will coordinate, collaborate, and cooperate across the CREID Network, including during outbreak events when rapid research action is needed. This implies that funded centers should be prepared to share information, align methods where appropriate, contribute to network-wide activities, and participate in joint efforts that strengthen the collective ability to respond quickly and effectively when new threats emerge.

Eligibility is broad and includes a wide range of domestic U.S. organizations and governmental entities, such as state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; and small businesses. The NOFO also highlights additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). That breadth reflects the program’s global outlook and its interest in building teams that can operate effectively across borders and sectors.

Key administrative details included in the source information are that this is a discretionary funding opportunity in the health category (CFDA 93.855), administered by NIH, with an original application closing date of June 21, 2024. The funding instrument is a cooperative agreement, which typically indicates substantial NIH involvement beyond standard grant oversight, often through coordination expectations, shared network goals, and active programmatic collaboration. The listed award ceiling is $350,000, signaling an upper limit referenced in the opportunity materials, and the record shows the notice was created on March 27, 2024.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers for Research in Emerging Infectious Diseases (CREID) Network (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
• This funding opportunity was created on 2024-03-27.
• Applicants must submit their applications by 2024-06-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $350,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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