Opportunity Information: Apply for W81XWH 19 CPMRP TRA

The DoD Chronic Pain Management Research Program (CPMRP) Translational Research Award (TRA) is a U.S. Department of Defense funding opportunity focused on moving solid, evidence-based chronic pain management findings closer to real-world use in clinical settings. The central goal is translation: taking what is already supported by credible research and accelerating its progression into practical clinical applications. That could include healthcare products, enabling technologies, or improvements that feed directly into clinical practice guidelines and standards of care. In other words, the program is not primarily looking for early-stage discovery work; it is looking for projects that help bridge the gap between existing evidence and routine care.

A key expectation for applications under this award is a clear explanation of how the proposed research will influence clinical practice. Proposals are expected to show a direct line from the planned work to the development, refinement, and/or revision of current standards of care, recommendations, or guidelines for managing chronic pain. Reviewers are likely looking for a well-argued path to impact: what clinical decision points or care pathways will change, what evidence will be generated to justify those changes, and how the work will support guideline developers, health systems, and clinicians in adopting improved approaches to chronic pain management.

At the same time, the opportunity places firm boundaries on what it will not support. Projects that aim to develop entirely new pharmacological therapies, or new non-pharmacological approaches, are not a fit if the effort is composed solely of a clinical trial. The mechanism is designed for translational work that may include clinical evaluation, but not proposals that are essentially "just a clinical trial" for a new intervention without the broader translational elements tied to implementation, practice standards, or guideline-relevant outcomes. In addition, clinical trials that evaluate opioid-based therapeutic interventions are explicitly prohibited, reflecting the program's constraints around opioid-focused treatment development and testing.

From an administrative standpoint, the opportunity is listed as a discretionary funding program under the Department of Defense, Department of the Army, administered through USAMRAA. The funding instrument types include both grants and cooperative agreements, indicating that some awards may involve more substantial agency involvement and coordination than a traditional standalone grant. The activity category is science and technology and other research and development, and the associated CFDA number is 12.420. Eligibility is described as unrestricted, meaning the competition is broadly open to many entity types, subject to any additional clarifications that may appear in the full announcement.

The original posting date for this specific opportunity was July 31, 2019, with an original closing date of December 6, 2019. The listing anticipated making about two awards. The stated award ceiling is shown as 0 in the provided source data, which typically means the ceiling was either not specified in that dataset extract or was to be defined elsewhere in the full funding announcement rather than implying no funding.

Overall, this Translational Research Award is best understood as a targeted mechanism for advancing evidence-based chronic pain management approaches into the kinds of outputs that change practice: clinically actionable products or tools, healthcare technologies that can be adopted in care delivery, and research findings packaged in a way that can directly support updates to guidelines and standards of care. The most competitive projects under this intent are those that do more than test an intervention; they generate the specific forms of evidence and implementation-relevant insight that help health systems and guideline bodies confidently improve how chronic pain is managed, while staying clear of opioid-intervention trials and avoiding a scope that is purely a standalone clinical trial for a novel therapy.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Chronic Pain Management Research Program, Translational Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Jul 31, 2019.
  • Applicants must submit their applications by Dec 06, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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