Ensuring Research Integrity - Research, Development, and Demonstration | IR ORI 22 001

Opportunity Information: Apply for IR ORI 22 001

The Ensuring Research Integrity - Research, Development, and Demonstration grant opportunity (Funding Opportunity Number IR ORI 22 001) is a discretionary grant program run by the U.S. Department of Health and Human Services (HHS) under the Office of the Assistant Secretary for Health (OASH), specifically through the Office of Research Integrity (ORI). It was announced for Fiscal Year 2022 funding authority under Section 301 of the Public Health Service Act (42 U.S.C. 241), which is commonly used as the legal basis for public health research and related federal support. The overall purpose is to strengthen research integrity across institutions that receive support from Public Health Service (PHS) funding components by backing practical, evidence-informed projects that help prevent research misconduct and improve how institutions promote and uphold responsible conduct of research.

At the center of this opportunity is the federal expectation that any institution receiving PHS research funding must maintain a research environment that actively promotes responsible conduct of research, supports integrity in research training and related activities, discourages research misconduct, and responds quickly and appropriately to allegations or evidence of potential misconduct. This requirement is grounded in the research misconduct regulation at 42 C.F.R. Part 93, including the institutional assurance and environment expectations described at 42 C.F.R. 93.300(c). ORI is positioning this program as a way to help institutions meet those regulatory obligations with real-world tools, tested approaches, and demonstrable improvements rather than only policy statements or one-time trainings.

The grant program is designed to support projects that fall into research, development, and demonstration. In practice, that means applicants can propose to study what works (research), build or refine solutions (development), and implement and evaluate them in realistic settings (demonstration). ORI emphasizes advancing the evolving field of research integrity, which suggests interest in modern challenges such as improving institutional processes for assessing allegations, reducing questionable research practices, strengthening mentorship and training cultures, and creating scalable educational and compliance resources. A strong proposal under this program would typically aim to produce tangible outcomes, such as new training curricula, assessment instruments, decision-support tools, model procedures, communication resources, or other practical deliverables that institutions can adopt to improve integrity and compliance with 42 C.F.R. Part 93.

This opportunity is tied broadly to the PHS research funding ecosystem. PHS funding components include units authorized to award grants and similar agreements for biomedical or behavioral research and research training. The notice lists examples such as NIH, CDC, FDA, SAMHSA, HRSA, IHS, AHRQ, ATSDR, OASH, and ASPR. Because many universities, medical centers, and research organizations depend on one or more of these funding streams, ORI is essentially targeting projects that can help institutions across that landscape meet shared integrity responsibilities and respond effectively when concerns arise.

From an administrative standpoint, the grant is categorized under Science and Technology and other Research and Development (CFDA 93.085). The maximum award amount (ceiling) is $150,000, and ORI anticipated making about 6 awards. The opportunity was created on December 22, 2021, with an original application closing date of March 15, 2022. Eligibility is labeled as "Others" with details to be clarified in an additional eligibility section in the full notice, which typically indicates that eligibility may extend beyond standard categories (for example, potentially including certain nonprofits, academic institutions, or other organizations suited to developing and testing integrity-focused resources), but the exact eligible applicant types would need to be verified in the full funding announcement.

In plain terms, this funding opportunity is meant to move research integrity work from general expectations into concrete, testable, shareable solutions. ORI is looking for projects that can strengthen education and outreach, improve prevention of misconduct, and enhance institutional readiness to handle allegations promptly and properly, while producing practical outputs that can be used by PHS-funded research institutions to better align with federal research misconduct regulations.

• The Department of Health and Human Services, Office of the Assistant Secretary for Health in the science and technology and other research and development sector is offering a public funding opportunity titled "Ensuring Research Integrity - Research, Development, and Demonstration" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.085.
• This funding opportunity was created on Dec 22, 2021.
• Applicants must submit their applications by Mar 15, 2022 No Explanation. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $150,000.00 in funding.
• The number of recipients for this funding is limited to 6 candidate(s).
• Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).

Apply for IR ORI 22 001

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